Which drug classification includes Diflucan, Lamisil, Lotrimin, Monistat, Nizoral, Terazol?

Which drug classification includes Diflucan, Lamisil, Lotrimin, Monistat, Nizoral, Terazol?

• A. Antibiotic
• B. Antihistamine
• C. Antifungal
• D. Antacid

Answer: (C)

These medicines are antifungals. They treat fungal infections by disrupting the fungi’s cell membrane, either by inhibiting ergosterol synthesis or by blocking key fungal enzymes. The listed drugs include several azoles (like fluconazole, ketoconazole, clotrimazole, miconazole, terconazole) and an allylamine (terbinafine). Azoles inhibit the enzyme that converts lanosterol to ergosterol, weakening the fungal membrane, while terbinafine blocks squalene epoxidase, causing toxic buildup and membrane disruption. Because their target is fungi—not bacteria, and not affecting stomach acid or allergy pathways—these drugs are classified as antifungals.

These medicines are antifungals. They treat fungal infections by disrupting the fungi’s cell membrane, either by inhibiting ergosterol synthesis or by blocking key fungal enzymes. The listed drugs include several azoles (like fluconazole, ketoconazole, clotrimazole, miconazole, terconazole) and an allylamine (terbinafine). Azoles inhibit the enzyme that converts lanosterol to ergosterol, weakening the fungal membrane, while terbinafine blocks squalene epoxidase, causing toxic buildup and membrane disruption. Because their target is fungi—not bacteria, and not affecting stomach acid or allergy pathways—these drugs are classified as antifungals.